[Effects of tramadol hydrochloride injection in relief of cancer pain].

Abstract

In a prospective multi-centre study, the pain-relieving effects of Tramadol Hydrochloride injection were observed in 98 patients with cancer pain. Tramadol was administered 100 mg intramuscularly p.r.n. for 1-3 days, and then the patients were crossed over to AP-237 injection (a common non-narcotic analgesic in China) or Tramal injection (product of Grunenthal) as control. The results showed that the response rates for Tramadol, Tramal and AP-237 were 82.6%, 81.8% and 62.1%, while the side effects were seen in 31%, 21% and 41%, respectively. In conclusion, the pain-relieving effect of Tramadol is as good as that of Tramal, but superior to AP-237.

• Authors: G Q Wu
• Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] (Zhonghua Zhong Liu Za Zhi) Vol. 15 Issue 4 Pg. 303-6 (Jul 1993) ISSN: 0253-3766 [Print] China
• PMID: 8174470 (Publication Type: English Abstract, Journal Article, Multicenter Study)

Chemical References

• Tramadol

Topics

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Female
• Humans
• Male
• Middle Aged
• Neoplasms (physiopathology)
• Pain, Intractable (drug therapy)
• Prospective Studies
• Tramadol (therapeutic use)