Adjunctive clonazepam treatment of tic symptoms in children with comorbid tic disorders and ADHD.

Abstract

The treatment of seven children and adolescents with a tic disorder and concomitant attention-deficit hyperactivity disorder (ADHD) is reviewed. Symptoms of ADHD were treated successfully with clonidine; however, patients experienced persistent tics. The patients were treated with the adjunctive use of clonazepam. The addition of clonazepam resulted in a further decrease in tic frequency and severity without affecting the coexisting ADHD symptoms. These cases suggest that clonazepam may be a useful adjunctive pharmacological intervention in treating tics in children with comorbid ADHD.

• Authors: R J Steingard, M Goldberg, D Lee, D R DeMaso
• Journal: Journal of the American Academy of Child and Adolescent Psychiatry (J Am Acad Child Adolesc Psychiatry) 1994 Mar-Apr Vol. 33 Issue 3 Pg. 394-9 ISSN: 0890-8567 [Print] United States
• PMID: 8169185 (Publication Type: Journal Article)

Chemical References

• Clonazepam
• Clonidine

Topics

• Adolescent
• Attention Deficit Disorder with Hyperactivity (complications, diagnosis)
• Child
• Child, Preschool
• Clonazepam (administration & dosage, adverse effects, therapeutic use)
• Clonidine (administration & dosage, therapeutic use)
• Comorbidity
• Drug Therapy, Combination
• Humans
• Psychiatric Status Rating Scales
• Tic Disorders (complications, diagnosis, drug therapy)
• Treatment Outcome