[Free radical retinal damage in rabbits of experimental acute ocular hypertension].

Abstract

The content of retinal malondialdehyde (MDA) in rabbits of experimental acute ocular hypertension was determined by thiobarbital fluorescence to demonstrate the presence of retinal damage due to free radicals, and to observe the therapeutic effect of vitamin E, the free radical scavenger. The results indicated that free radicals participated in the retinal damage in acute ocular hypertension, and vitamin E was therapeutically effective for treatment.

• Authors: G Q Zhao
• Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology (Zhonghua Yan Ke Za Zhi) Vol. 29 Issue 5 Pg. 293-5 (Sep 1993) ISSN: 0412-4081 [Print] China
• PMID: 8168396 (Publication Type: English Abstract, Journal Article)

Chemical References

• Free Radical Scavengers
• Free Radicals
• Vitamin E
• Malondialdehyde

Topics

• Animals
• Female
• Free Radical Scavengers
• Free Radicals
• Male
• Malondialdehyde (metabolism)
• Ocular Hypertension (drug therapy, metabolism)
• Rabbits
• Retina (metabolism, pathology)
• Vitamin E (therapeutic use)