| Abstract | The aim of this experimental study was to examine two new wound healing adjuvants. Four experimental wounds were created on the back of rabbits to compare the kinetics of wound healing after applying the standard treatment, Silastic gel, and elastomer with and without compounds known to act on wound healing. We observed a tendency towards more rapid healing in the gel groups (13.7 days), the elastomer group (17.3 days) and the elastomer with active compound group (15.3 days) compared with the control group (17.3 days) and the standard treatment group (17.8 days). The differences were not however statistically different. Elastomer is the better carrier for active wound healing compounds because it has better stability over time. Silicon dressings are interesting for wound healing because they give satisfactory results in terms of healing time and in terms of redressing and patient comfort. |
| Authors | J P Aubert, G Magalon
(Affiliation: Service de Chirurgie Plastique, Hôpital de la Conception, Marseille.)
|
| Journal | Journal de chirurgie
(J Chir (Paris))
Vol. 130
Issue 12
Pg. 533-8
(Dec 1993)
ISSN: 0021-7697 FRANCE |
| Vernacular Title | Le gel et l'élastomère de Silastic dans la cicatrisation des plaies chez le lapin. |
| PMID | 8163619
(Publication Type: Comparative Study, English Abstract, Journal Article)
|
| Chemical References |
- Drug Combinations
- Gels
- Silicone Elastomers
- Fluocinonide
- Fusidic Acid
- Deoxyribonucleases
- Plasmin
|
| Topics |
- Animals
- Deoxyribonucleases
(pharmacology)
- Disease Models, Animal
- Drug Combinations
- Drug Evaluation, Preclinical
- Female
- Fluocinonide
(pharmacology)
- Fusidic Acid
(pharmacology)
- Gels
- Plasmin
(pharmacology)
- Rabbits
- Silicone Elastomers
(pharmacology)
- Wound Healing
(drug effects)
|
