Abstract |
Comparative analysis of serum DNA content in healthy rats, rats with experimental alloxan diabetes, and the rats with the diabetes compensated by transplantation of the embryonal pancreas into the anterior chamber of the eye. In the course of diabetes the concentration of free-circulating serum DNA reliably increase 10-12 times, and the compensation of the diabetes returns it to the norm. The revealed relationship may be used for diagnostics of initiation and full compensation of the insulin-dependent diabetes.
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Authors | O E Trubetskaia, A V Kulikov, G V Afanas'eva, K Iu Reznikov |
Journal | Izvestiia Akademii nauk. Seriia biologicheskaia
(Izv Akad Nauk Ser Biol)
1994 Jan-Feb
Issue 1
Pg. 152-5
ISSN: 1026-3470 [Print] Russia (Federation) |
Vernacular Title | Giperproduktsiia DNK v plazme krovi u zhivotnykh s éksperimental'nym diabetom i ee kompensatsiia s pomoshch'iu transplantatsii insulinprodutsiruiushcheÄ tkani v peredniuiu kameru glaza. |
PMID | 8161918
(Publication Type: Comparative Study, English Abstract, Journal Article)
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Chemical References |
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Topics |
- Animals
- Anterior Chamber
- DNA
(blood)
- Diabetes Mellitus, Experimental
(blood, surgery)
- Electrophoresis, Agar Gel
- Fetal Tissue Transplantation
- Islets of Langerhans Transplantation
- Rats
- Rats, Wistar
- Transplantation, Heterotopic
- Transplantation, Homologous
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