Abstract |
A 44-year-old German fell ill in Libya, where he had been living for 10 years, with high fever, rigor and a nonitching centrifugally spreading macular rash, which had spared the head, hands and soles. In addition, a systolic cardiac murmur was heard. The Weil-Felix reaction had a titre rising within 3 days from 1:160 to 1:640, confirming the diagnosis of rickettsial disease, the total clinical picture indicating typhus. On treatment with chloramphenicol (1 g three times daily i.v.) the fever subsided within 5 days. On the ninth day treatment was changed to oral doxycyclin, 200 mg daily for 3 weeks. Echocardiography surprisingly revealed a floating thrombus, about 4 x 8 cm, attached to the hypo- and even akinetic apex of the left ventricle. In addition there was single-vessel coronary disease. Since the segmental contraction abnormality persisted after the typhus had been cured, a causal connection with the rickettsial disease is unlikely. The thrombus was removed at the time of a aortocoronary bypass operation: his course has been unremarkable since then.
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Authors | G Sitzler, U J Winter, G Peters, T Gheorghiu, H H Hilger |
Journal | Deutsche medizinische Wochenschrift (1946)
(Dtsch Med Wochenschr)
Vol. 119
Issue 12
Pg. 418-22
(Mar 25 1994)
ISSN: 0012-0472 [Print] Germany |
Vernacular Title | Rickettsiose vom Fleckfiebertyp. Gemeinsames Auftreten mit einem linksventrikulären Thrombus und einer koronaren Ein-Gefäss-Krankheit. |
PMID | 8143556
(Publication Type: Case Reports, English Abstract, Journal Article, Review)
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Topics |
- Adult
- Combined Modality Therapy
- Coronary Disease
(diagnosis, therapy)
- Diagnosis, Differential
- Drug Therapy, Combination
- Exanthema
(diagnosis, drug therapy)
- Germany
(ethnology)
- Heart Diseases
(diagnosis, therapy)
- Heart Ventricles
- Humans
- Libya
- Male
- Thrombosis
(diagnosis, therapy)
- Typhus, Epidemic Louse-Borne
(diagnosis, drug therapy)
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