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Pontine infarction in acute posterior multifocal placoid pigment epitheliopathy.

AbstractIn a patient with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), a pontine infarction occurred about 6 months after the ophthalmological manifestation. We report the first case with histopathologically proven vasculitis shown by muscle biopsy and the first positron emission tomographic documentation in APMPPE. The ophthalmological and cerebral symptoms responded well to steroid treatment. Long-term immunosuppression (e.g. azathioprine 1-2 mg/kg) seems to decrease the risk of recurrent systemic vasculitis.
AuthorsH Bewermeyer, G Nelles, M Huber, C Althaus, E Neuen-Jacob, J Assheuer (Affiliation: Neurologische Klinik, Städtischen Krankenhauses Leverkusen, Germany.)
JournalJournal of neurology (J Neurol) Vol. 241 Issue 1 Pg. 22-6 (Nov 1993) ISSN: 0340-5354 GERMANY
PMID8138817 (Publication Type: Case Reports, Journal Article)
Topics
  • Acute Disease
  • Adult
  • Arterioles
  • Cerebral Infarction (etiology, radionuclide imaging)
  • Choroid Diseases (complications)
  • Conjunctivitis, Viral (complications)
  • Fluorescein Angiography
  • Humans
  • Ischemia (etiology)
  • Male
  • Pigment Epithelium of Eye (blood supply)
  • Pons (blood supply, radionuclide imaging)
  • Tomography, Emission-Computed
  • Vasculitis (complications)