[Relation between DNA content in ovarian cystadenoma and its pathohistology].

Abstract

DNA index and cell cycle distribution were studied by flow cytometry in 32 cases of ovarian borderline cystadenoma, 16 ovarian cystadenocarcinoma and 12 ovarian benign cystadenoma, and their relations to pathological patterns of the diseases were inquired. The results showed that the DNA index and S+G2M phase in cell cycle of the diseases were related to their pathological patterns. The DNA index and S+G2M cell were increased by turn from benign to borderline and to malignant tumor. DNA index and cell cycle distribution might be valuable in reflecting the biological behavior of deteriorating ovarian cystadenoma. The authors consider that determination of DNA content and cell cycle could be biological indexes of supplementary diagnosis for the deterioration of borderline tumor.

• Authors: Z C Sun
• Journal: Zhonghua fu chan ke za zhi (Zhonghua Fu Chan Ke Za Zhi) Vol. 28 Issue 12 Pg. 731-3, 760-1 (Dec 1993) ISSN: 0529-567X [Print] China
• PMID: 8137645 (Publication Type: English Abstract, Journal Article)

Chemical References

• DNA, Neoplasm

Topics

• Cell Cycle
• Cystadenocarcinoma, Mucinous (genetics, pathology)
• Cystadenocarcinoma, Serous (genetics, pathology)
• Cystadenoma (genetics, pathology)
• DNA, Neoplasm (analysis)
• Female
• Flow Cytometry
• Humans
• Ovarian Neoplasms (genetics, pathology)