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A case of rhinoscleroma cured with ciprofloxacin.

Abstract
The diagnosis of rhinoscleroma was confirmed in a 17-year-old female patient from Tehran, Iran, suffering from a roundish tumour of the nose. Prior treatment with streptomycin and tetracycline had been unsuccessful. A three-month course of high-dose oral ciprofloxacin (750 mg b.i.d.) led to prompt cessation of the growth of the granuloma which was removed later by plastic surgery. Although serology alone appeared to have little value for the specific diagnosis of rhinoscleroma, a significant increase of IgG antibodies during treatment with ciprofloxacin confirmed infection by Klebsiella rhinoscleromatis in this case.
AuthorsM Trautmann, T Held, M Ruhnke, N Schnoy
JournalInfection (Infection) 1993 Nov-Dec Vol. 21 Issue 6 Pg. 403-6 ISSN: 0300-8126 [Print] Germany
PMID8132373 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antibodies, Bacterial
  • Ciprofloxacin
Topics
  • Adolescent
  • Antibodies, Bacterial (blood)
  • Ciprofloxacin (therapeutic use)
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Klebsiella pneumoniae (immunology)
  • Rhinoplasty
  • Rhinoscleroma (drug therapy, immunology)

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