[The combined therapy of patients with gonorrheal-chlamydial urogenital infections by leukinferon immunocorrection].

Abstract

The adjuvant injection of wide-spectrum immunocorrector leukinferon to 45 males with gonorrheal-chlamydial urogenital infection receiving tarivid and doxicicline made the treatment shorter and the number of inflammatory complications and recurrences less numerous. Leukocyte and lymphocyte counts returned to normal values 6 days earlier and so did immunological indices. In control subjects (20 patients) on immunocorrection with tactivin inflammation persisted longer, urogenital complications were not cured, chlamydial recurrences occurred in 10% of the patients, immunological normalization was not reached.

• Authors: V P Kuznetsov, V V Dubenskiĭ, V V Delektorskiĭ, Iu M Igoshin, D L Beliaev, G N Iashkova, A A Babaiants
• Journal: Terapevticheskii arkhiv (Ter Arkh) Vol. 65 Issue 11 Pg. 39-42 ( 1993) ISSN: 0040-3660 [Print] Russia (Federation)
• Vernacular Title: Kompleksnaia terapiia bol'nykh s gonoreĭno-khlamidiĭnoĭ urogenital'noĭ infektsieĭ s immunokorrektsieĭ leĭkinferonom.
• PMID: 8108795 (Publication Type: Case Reports, Comparative Study, English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Cytokines
• Drug Combinations
• Interferon Type I
• leukinferon
• Ofloxacin
• Doxycycline

Topics

• Adjuvants, Immunologic (therapeutic use)
• Adolescent
• Adult
• Chlamydia Infections (complications, drug therapy, immunology)
• Cytokines (therapeutic use)
• Doxycycline (therapeutic use)
• Drug Combinations
• Drug Therapy, Combination (therapeutic use)
• Gonorrhea (complications, drug therapy, immunology)
• Humans
• Immunity, Cellular (drug effects)
• Interferon Type I (therapeutic use)
• Male
• Male Urogenital Diseases (complications, drug therapy, immunology)
• Ofloxacin (therapeutic use)