HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Pathophysiology and current therapy of congestive heart failure due to idiopathic cardiomyopathy].

Abstract
Congestive heart failure (CHF) due to idiopathic cardiomyopathy is reviewed. CHF in dilated cardiomyopathy (DCM) is caused mainly by myocardial systolic dysfunction. Diuretics, angiotensin-converting enzyme (ACE) inhibitors and digitalis are the first choice drugs. ACE inhibitors have been shown to be effective in prolonging life and improving quality of life. Recently, long-term beta-blockade therapy has been shown to be useful. CHF in hypertrophic cardiomyopathy (HCM) is caused by decreased myocardial compliance. The beneficial effect of verapamil in HCM is related to improved relaxation and diastolic filing. Verapamil is also effective in relieving myocardial ischemia. Beta-blockade decreases pressure gradient and oxygen consumption. Idiopathic restrictive cardiomyopathy is a very rare disease and decreased myocardial compliance is responsible for CHF.
AuthorsM Kambayashi, T Kumada
JournalNihon rinsho. Japanese journal of clinical medicine (Nihon Rinsho) Vol. 51 Issue 5 Pg. 1328-32 (May 1993) ISSN: 0047-1852 [Print] Japan
PMID8101239 (Publication Type: English Abstract, Journal Article, Review)
Chemical References
  • Adrenergic beta-Antagonists
  • Calcium Channel Blockers
  • Vasodilator Agents
Topics
  • Adrenergic beta-Antagonists (therapeutic use)
  • Calcium Channel Blockers (therapeutic use)
  • Cardiomyopathies (complications)
  • Digitalis
  • Heart Failure (drug therapy, etiology)
  • Humans
  • Plants, Medicinal
  • Plants, Toxic
  • Vasodilator Agents (therapeutic use)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: