Rapid resolution of tuberculous pericardial effusions with high dose prednisone and anti-tuberculous drugs.

• Abstract: Ten patients with tuberculous pericardial effusion, treated initially with adjunctive prednisone 120 mg daily, improved dramatically within a week. There were no complications. Such rapid resolution suggests that the duration of prednisone treatment for this condition could be shortened, which may be important in HIV seropositive patients.
• Authors: J I Strang (Affiliation: Cecilia Makiwane Hospital, Mdantsane, Ciskei, South Africa.)
• Journal: The Journal of infection (J Infect) Vol. 28 Issue 3 Pg. 251-4 (May 1994) ISSN: 0163-4453 [Print] ENGLAND
• PMID: 8089513 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antitubercular Agents
• Rifampin
• Prednisone
• Isoniazid

Topics

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Antitubercular Agents (administration & dosage, therapeutic use)
• Female
• HIV Seronegativity
• Humans
• Isoniazid (administration & dosage, therapeutic use)
• Male
• Middle Aged
• Mycobacterium tuberculosis (isolation & purification)
• Pericardial Effusion (drug therapy, microbiology)
• Pericarditis, Tuberculous (drug therapy, microbiology)
• Prednisone (administration & dosage, therapeutic use)
• Rifampin (administration & dosage, therapeutic use)