Abstract |
We report a case of drug induced pneumonitis caused by Saiboku-To. A 60-year-old woman was admitted to our hospital because of dry cough, fever and severe dyspnea after taking Saiboku-To. Blood gas analysis showed marked hypoxemia. Chest X-ray obtained on admission showed diffuse ground glass shadows in bilateral lung fields, and computed tomography showed diffuse interstitial shadows. Following steroid pulse therapy, clinical symptoms, hypoxemia and chest X-ray findings were ameliorated. Against medical advice, she took another Chinese medicine with ingredients similar to those of Saiboku-To. She complained of dry cough, fever and dyspnea and the chest X-ray again revealed diffuse ground glass shadows in both lung fields. Lymphocyte stimulation test against Saiboku-To and the patch test for Saiboku-To were positive. Therefore, we diagnosed this case as having pneumonitis due to Saiboku-To. This is first report of interstitial pneumonitis due to Saiboku-To.
|
Authors | R Temaru, N Yamashita, S Matsui, T Ohta, A Kawasaki, M Kobayashi |
Journal | Nihon Kyobu Shikkan Gakkai zasshi
(Nihon Kyobu Shikkan Gakkai Zasshi)
Vol. 32
Issue 5
Pg. 485-90
(May 1994)
ISSN: 0301-1542 [Print] Japan |
PMID | 8084106
(Publication Type: Case Reports, English Abstract, Journal Article)
|
Chemical References |
- Drugs, Chinese Herbal
- saiboku-to
|
Topics |
- Alveolitis, Extrinsic Allergic
(chemically induced)
- Drugs, Chinese Herbal
(adverse effects)
- Female
- Humans
- Medicine, Kampo
- Middle Aged
|