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[A case of drug induced pneumonitis caused by saiboku-To].

Abstract
We report a case of drug induced pneumonitis caused by Saiboku-To. A 60-year-old woman was admitted to our hospital because of dry cough, fever and severe dyspnea after taking Saiboku-To. Blood gas analysis showed marked hypoxemia. Chest X-ray obtained on admission showed diffuse ground glass shadows in bilateral lung fields, and computed tomography showed diffuse interstitial shadows. Following steroid pulse therapy, clinical symptoms, hypoxemia and chest X-ray findings were ameliorated. Against medical advice, she took another Chinese medicine with ingredients similar to those of Saiboku-To. She complained of dry cough, fever and dyspnea and the chest X-ray again revealed diffuse ground glass shadows in both lung fields. Lymphocyte stimulation test against Saiboku-To and the patch test for Saiboku-To were positive. Therefore, we diagnosed this case as having pneumonitis due to Saiboku-To. This is first report of interstitial pneumonitis due to Saiboku-To.
AuthorsR Temaru, N Yamashita, S Matsui, T Ohta, A Kawasaki, M Kobayashi
JournalNihon Kyobu Shikkan Gakkai zasshi (Nihon Kyobu Shikkan Gakkai Zasshi) Vol. 32 Issue 5 Pg. 485-90 (May 1994) ISSN: 0301-1542 [Print] Japan
PMID8084106 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Drugs, Chinese Herbal
  • saiboku-to
Topics
  • Alveolitis, Extrinsic Allergic (chemically induced)
  • Drugs, Chinese Herbal (adverse effects)
  • Female
  • Humans
  • Medicine, Kampo
  • Middle Aged

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