[Severe contact dermatitis caused by Parfenac cream].

Abstract

Bufexamac is an anti-inflammatory agent used as topical treatment of various pruritic diseases. Since it was put on the market, this product has been blamed for the occurrence of contact dermatitis (eczema, urticaria) and, rarely, severe toxicodermia. We report a case of severe contact dermatitis developed after application of bufexamac (Parfenac) cream. Patch-tests performed two months after the acute phase were positive (+ + +) for both Parfenac cream and bufexamac.

• Authors: E Collet, M Lacroix, C Boulitrop Morvan, S Dalac, J Sallin, D Lambert
• Journal: Annales de dermatologie et de venereologie (Ann Dermatol Venereol) Vol. 120 Issue 12 Pg. 892-3 ( 1993) ISSN: 0151-9638 [Print] France
• Vernacular Title: Dermite de contact grave à la crème Parfenac.
• PMID: 8074349 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Bufexamac

Topics

• Bufexamac (administration & dosage, adverse effects)
• Dermatitis, Contact (etiology, pathology)
• Drug Eruptions (etiology, pathology)
• Female
• Humans
• Middle Aged
• Patch Tests