Abstract |
Immunoprecipitation of the purified 160-kDa complement regulatory protein of Trypanosoma cruzi by Chagas' disease patient sera was examined as a possible correlate of the complement-mediated lysis test and as an indicator of parasite clearance. The results presented demonstrate that assessment of the humoral response to this antigen is a useful indicator of parasite clearance and may be particularly helpful in the assessment of some patients for whom other serological tests produce ambiguous results.
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Authors | K A Norris, L M Galvão, J E Schrimpf, J R Cançado, A U Krettli |
Journal | Infection and immunity
(Infect Immun)
Vol. 62
Issue 9
Pg. 4072-4
(Sep 1994)
ISSN: 0019-9567 [Print] United States |
PMID | 8063427
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Antibodies, Protozoan
- Protozoan Proteins
- Complement System Proteins
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Topics |
- Animals
- Antibodies, Protozoan
(blood)
- Chagas Disease
(immunology, parasitology)
- Complement System Proteins
(immunology)
- Humans
- Protozoan Proteins
(immunology)
- Trypanosoma cruzi
(immunology)
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