Fatal group A streptococcal meningitis and toxic shock-like syndrome: case report.

Abstract

A previously healthy 8-year-old girl presented with flu-like symptoms, developed toxic shock-like syndrome, and died within 48 hours. At autopsy she was found to have purulent meningitis. The group A beta-hemolytic streptococcus isolated from her CSF was a member of clone ET 2. This strain produced a variant form of streptococcal pyrogenic exotoxin A (SPEA 2) that has recently been associated with widespread toxic shock-like syndrome.

• Authors: G P Jevon, W M Dunne Jr, H K Hawkins, D L Armstrong, J M Musser
• Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (Clin Infect Dis) Vol. 18 Issue 1 Pg. 91-3 (Jan 1994) ISSN: 1058-4838 [Print] United States
• PMID: 8054439 (Publication Type: Case Reports, Journal Article)

Topics

• Brain (microbiology, pathology)
• Child
• Fatal Outcome
• Female
• Humans
• Meningitis, Bacterial (cerebrospinal fluid, microbiology, pathology)
• Shock, Septic (cerebrospinal fluid, microbiology)
• Streptococcal Infections (cerebrospinal fluid, pathology)
• Streptococcus pyogenes