Leuprolide acetate for exhibitionism in Huntington's disease.

Abstract

We treated a patient with Huntington's disease and exhibitionism using leuprolide acetate (Lupron Depot, TAP Pharmaceuticals), a gonadotropin-releasing hormone agonist. The result was elimination of his deviant sexual behavior with few side effects. This regimen may be a safe and effective pharmacological treatment of the paraphilias. The occurrence of paraphilias in basal ganglia disorders is reviewed.

• Authors: S S Rich, F Ovsiew
• Journal: Movement disorders : official journal of the Movement Disorder Society (Mov Disord) Vol. 9 Issue 3 Pg. 353-7 (May 1994) ISSN: 0885-3185 [Print] United States
• PMID: 8041380 (Publication Type: Case Reports, Journal Article)

Chemical References

• Delayed-Action Preparations
• Leuprolide

Topics

• Adult
• Delayed-Action Preparations
• Dementia (drug therapy, genetics, psychology)
• Exhibitionism (drug therapy, psychology)
• Humans
• Huntington Disease (drug therapy, genetics, psychology)
• Injections, Intramuscular
• Leuprolide (adverse effects, therapeutic use)
• Male
• Neurologic Examination (drug effects)