[The clinical and microbiological study of the preparation perfloxacin in treating urologic infections].

Abstract

Experience with Pefloxacin treatment of thirty-nine patients presenting urinary tract infection, over the period 1992-1993, is shared. The drug is administered per os at dosage--800 mg, divided in two doses given at 12-hour intervals. As shown by the results of assaying the clinical symptoms, laboratory indicators and microbiological findings in the urine, the therapeutic effect is very good. A clinical cure is recorded in 76 cases (92 per cent), and healing of the bacteriological agent--in 92.31 per cent. Side effects are rarely observed and mildly manifested. The results of Pefloxacin treatment warrant the assumption that the drug synthesized is encouraging, suitable for both out- and inpatient treatment of urinary tract infections, and therefore it should be introduced in the daily routine practice.

• Authors: D Dragiev, E Savov, A Lilov, Z Tsenova, I Saltirov, I Atanasova
• Journal: Khirurgiia (Khirurgiia (Sofiia)) Vol. 46 Issue 4 Pg. 49-51 ( 1993) ISSN: 0450-2167 [Print] Bulgaria
• Vernacular Title: Klinichno i mikrobiologichno prouchvane na preparata pefloksatsin pri lechenie na uroinfektsiite.
• PMID: 8041098 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• 4-Quinolones
• Anti-Infective Agents
• Fluoroquinolones
• Quinolones
• perfloxacin

Topics

• 4-Quinolones
• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Anti-Infective Agents (adverse effects, therapeutic use)
• Bacteria (drug effects, isolation & purification)
• Bacteriuria (drug therapy, microbiology)
• Drug Tolerance
• Fluoroquinolones
• Humans
• Microbial Sensitivity Tests
• Middle Aged
• Quinolones (adverse effects, therapeutic use)
• Urinary Tract Infections (drug therapy, microbiology)