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[The effect of temporary skin substitutes on the area around the wound following an experimental thermal burn of the skin].

Abstract
The effect of temporary skin resurfacing on processes developing in the skin surrounding post-thermal-burn wounds is morphologically studied in experiment. The burned wound region and perilesional area are immediately covered by a fresh allograft, xenograft, Ampoxen, Pharmexplant and Deflamol ointment. Tissue specimens for histological evaluation are taken within 3, 7 and 14 days. The processes developing within the wound and in the perilesional area under a fresh allograft and Deflamol ointment appear to be the most beneficial. Here the inflammatory response is substantially milder, and regardless of the latter, the regeneration and even differentiation of cells in the course of healing are more clearcut, as compared to the other resurfacing methods used in the experiment.
AuthorsK Troshev, D Markov
JournalKhirurgiia (Khirurgiia (Sofiia)) Vol. 46 Issue 4 Pg. 40-2 ( 1993) ISSN: 0450-2167 [Print] Bulgaria
Vernacular TitleVŭzdeĭstvie na vremenni kozhni zamestiteli vŭrkhu okoloraneva zona sled eksperimentalno toplinno izgariane na kozhata.
PMID8041094 (Publication Type: Comparative Study, English Abstract, Journal Article)
Topics
  • Animals
  • Burns (pathology, therapy)
  • Evaluation Studies as Topic
  • Necrosis
  • Rats
  • Skin (injuries, pathology)
  • Skin Transplantation
  • Skin, Artificial
  • Time Factors
  • Wound Healing

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