Abstract | PURPOSE: We describe for the first time the case of a child with Kawasaki syndrome and associated transient erythroblastopenia. PATIENTS AND METHODS: RESULTS: The anemia and reticulocytopenia resolved with normalization of her hemoglobin. The platelet count increased and she developed a thrombocytosis characteristic of this clinical entity. She completely recovered without recurrence of either the anemia or reticulocytopenia. CONCLUSIONS: We speculate that the cause of the erythroblastopenia and thrombocytopenia is an inflammatory insult of Kawasaki syndrome on the bone marrow and its various lineages causing the myriad hematological abnormalities now associated with Kawasaki syndrome. It is possible that the i.v. immunoglobulin aids in neutralizing the triggering agent and therefore shortening the duration of the marrow insult.
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Authors | G R Frank, I Cherrick, G Karayalcin, E Valderrama, P Lanzkowsky |
Journal | The American journal of pediatric hematology/oncology
(Am J Pediatr Hematol Oncol)
Vol. 16
Issue 3
Pg. 271-4
(Aug 1994)
ISSN: 0192-8562 [Print] United States |
PMID | 8037349
(Publication Type: Case Reports, Journal Article)
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Topics |
- Female
- Humans
- Infant
- Mucocutaneous Lymph Node Syndrome
(complications)
- Red-Cell Aplasia, Pure
(etiology)
- Thrombocytopenia
(etiology)
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