Diagnostic value of indirect pancreatic function test in serum of anuric patients with chronic renal failure.

Abstract

Although patients with chronic renal failure have a high incidence of chronic pancreatic disease, the condition is frequently overlooked. We have modified the pancreolauryl test--an indirect pancreatic function test--for anuric patients. The test permitted good discrimination between patients with chronic pancreatic disease and those with a normal pancreas when serum levels of fluorescein were measured 10 h after administration with a standard meal. The sensitivity at this time interval was 80% and the specificity 83%. We conclude that the pancreolauryl test with serum measurements provides a simple, noninvasive, and reliable diagnostic test for chronic pancreatic disease in anuric patients with chronic renal failure.

• Authors: M M Lerch, I Nolte, J Riehl, U Gladziwa, H Mann, H G Sieberth, S Matern
• Journal: Scandinavian journal of clinical and laboratory investigation (Scand J Clin Lab Invest) Vol. 54 Issue 3 Pg. 247-50 (May 1994) ISSN: 0036-5513 [Print] England
• PMID: 8036450 (Publication Type: Journal Article)

Chemical References

• Fluoresceins

Topics

• Anuria (blood, complications)
• Chronic Disease
• Fluoresceins (analysis)
• Humans
• Kidney Failure, Chronic (blood, complications)
• Middle Aged
• Pancreatic Diseases (blood, complications, diagnosis, urine)