Abstract |
The biospecific antiproteinase haemosorbent (BAH) ' Ovosorb' containing, in the bulk of polyacryamide gel, the ovomucoid from whites of duck eggs, was used for a complex treatment of the experimental generalized purulent peritonitis and acute destructive pancreatitis in dogs. The efficiency of BAH was manifested in the significant reduction of lethality of the experimental animals, a more rapid liquidation of proteinasaemia, normalization in plasma of alpha 1-proteinase inhibitor and protein metabolism. Thus, by eliminating proteinases from circulation, Ovosorb contributes to the cessation of imbalance in the proteinase-inhibitor system and is efficient in the therapy of pathological states related to this imbalance.
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Authors | N A Platé, V V Kirkovsky, O F Antiperovich, V V Nicolaichik, T A Valueva, S B Sinilo, V M Moin, G A Lobacheva |
Journal | Biomaterials
(Biomaterials)
Vol. 15
Issue 4
Pg. 285-8
(Mar 1994)
ISSN: 0142-9612 [Print] Netherlands |
PMID | 8031989
(Publication Type: Journal Article)
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Chemical References |
- Protease Inhibitors
- Ovosorb
- Ovomucin
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Topics |
- Acute Disease
- Animals
- Dogs
- Ovomucin
(therapeutic use)
- Pancreatitis
(drug therapy, metabolism)
- Peritonitis
(drug therapy, metabolism)
- Protease Inhibitors
(therapeutic use)
- Suppuration
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