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Myocardial salvage by chimyl alcohol: possible role of peroxisomal dysfunction in reperfusion injury.

Abstract
The results of this study suggest that reperfusion of ischemic myocardium may lead to the peroxisomal disorder both functionally and biochemically. An alkyl glycerol such as chimyl alcohol can protect the ischemic heart from the reperfusion injury probably by enhancing the plasmalogen synthesis.
AuthorsN Maulik, A Tosaki, R M Engelman, G A Cordis, D K Das
JournalAnnals of the New York Academy of Sciences (Ann N Y Acad Sci) Vol. 723 Pg. 380-4 (Jun 17 1994) ISSN: 0077-8923 [Print] United States
PMID8030890 (Publication Type: Journal Article)
Chemical References
  • Glyceryl Ethers
  • Plasmalogens
  • Catalase
  • chimyl alcohol
Topics
  • Animals
  • Catalase (metabolism)
  • Glyceryl Ethers (pharmacology)
  • Microbodies (physiology)
  • Myocardial Reperfusion Injury (physiopathology, prevention & control)
  • Plasmalogens (metabolism)
  • Rats
  • Rats, Sprague-Dawley

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