[An analysis of the results of clinical trials of praziquantel analogs in intestinal cestode and trematode infections. 2. The treatment of liver trematode infections (opisthorchiasis, fascioliasis) and schistosomiasis].

Abstract

The authors did not detect any differences in the efficacies and tolerance of praziquantel analogs manufactured by various firms (azinox, Russia; pikitor, China; cesol, cisticide, biltricide, Bayer, Merk, Germany, India). These drugs were found highly effective in opisthorchiasis (87.8%) and schistosomiasis (91.7%) and ineffective in fascioliasis. The efficacy and tolerance of azinox, a drug manufactured in this country, was similar to those of its foreign analogs.

• Authors: A M Bronshteĭn, L I Mel'nikova, R A Firsova, Iu A Legon'kov
• Journal: Meditsinskaia parazitologiia i parazitarnye bolezni (Med Parazitol (Mosk)) 1993 Mar-Apr Issue 2 Pg. 16-7 ISSN: 0025-8326 [Print] Russia (Federation)
• Vernacular Title: Analiz rezul'tatov klinicheskikh ispytaniĭ analogov prazikvantelia pri kishechnykh tsestodozakh i trematodozakh. Soobshchenie 2. Lechenie trematodozov pecheni (opistorkhoz i fastsiolez) i shistosomozov.
• PMID: 8028557 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article)

Chemical References

• Praziquantel

Topics

• Adolescent
• Adult
• Aged
• Cestode Infections (drug therapy)
• Child
• Child, Preschool
• Fascioliasis (drug therapy)
• Female
• Humans
• Intestinal Diseases, Parasitic (drug therapy)
• Liver Diseases, Parasitic (drug therapy)
• Male
• Middle Aged
• Opisthorchiasis (drug therapy)
• Praziquantel (adverse effects, analogs & derivatives, therapeutic use)
• Schistosomiasis (drug therapy)