Evaluation of a DNA probe assay (Gen-Probe PACE 2) as the test of cure for Neisseria gonorrhoeae genital infections.

Abstract

A DNA probe (Gen-Probe PACE 2) detects portions of viable and nonviable organisms, and test results could remain positive after effective treatment of genital Neisseria gonorrhoeae infection. Twenty patients underwent test-of-cure studies 6 to 11 days after standard treatment for gonorrhea; in each case the DNA probe finding was negative. The Gen-Probe PACE 2 probe is reliable for test-of-cure study as early as 6 days after treatment.

• Authors: J W Hanks, C T Scott, C E Butler, D W Wells
• Journal: The Journal of pediatrics (J Pediatr) Vol. 125 Issue 1 Pg. 161-2 (Jul 1994) ISSN: 0022-3476 [Print] United States
• PMID: 8021769 (Publication Type: Journal Article)

Chemical References

• DNA Probes
• DNA, Bacterial
• Ceftriaxone

Topics

• Adolescent
• Adult
• Bacteriological Techniques
• Ceftriaxone (therapeutic use)
• DNA Probes
• DNA, Bacterial (analysis)
• Evaluation Studies as Topic
• Female
• Gonorrhea (diagnosis, drug therapy)
• Humans
• Male
• Prospective Studies
• Treatment Outcome