The
AIDS-committee of The Danish Society of Paediatrics has done a nation-wide study among infants and children under the age of 15 with
AIDS or
HIV-antibodies in preparation for planning prevention and treatment. Clinical data have been collected from the Departments of Paediatrics and
Infectious Diseases,
Haemophilia, Dermatology and Internal Medicine up to 1 March 1993. The study includes 44 infants with a risk of vertical transmission from the mother and 16 children with
haemophilia. No cases were found to be infected by
blood-transfusion. Twenty of the 44 infants with congenital
HIV-antibodies were HIV-infected. Seven of them died from
AIDS, 10 currently have
AIDS and three are asymptomatic. Seventeen infants are well and HIV-antibody negative after the age of 18 months. Seven infants still have unclarified status, but all are well. Three of the patients with
haemophilia are dead. The 13 others do not have
AIDS. It is surprising that most of the infected infants' mothers were not known to be infected before the infants got sick. Thus infected infants exist in families who are not suspected to be HIV-infected. The
AIDS-committee of The Danish Society of Paediatrics has proposed recommendations for HIV-testing of infants and children. HIV-infected families need comprehensive psychosocial care. The risk-factor from
blood-transfusion is now eliminated, but vertical transmission will continue to be a risk-factor. The size of the problem in Denmark will not be known until an epidemiological study of pregnant women has been conducted.