Chronic sensorimotor polyneuropathy associated with cerebello-extrapyramidal manifestations in a patient with tomaculous neuropathy.

Abstract

Clinical, electrophysiological and morphological (sural nerve and gastrocnemius muscle biopsies) data of a 57-year-old man with a chronic sensorimotor polyneuropathy of Charcot-Marie-Tooth type associated with a progressive cerebello-extrapyramidal syndrome are reported. Patient's family data were negative. Nerve structural and ultrastructural examinations revealed the morphological picture of a tomaculous neuropathy. The association of different clinical syndromes and the specificity of the tomaculous neuropathy are discussed.

• Authors: M Macovei, M Alexianu, C Vasilescu, M E Alexianu, A Dan, B Burghelea
• Journal: Romanian journal of neurology and psychiatry = Revue roumaine de neurologie et psychiatrie (Rom J Neurol Psychiatry) Vol. 31 Issue 3-4 Pg. 279-81 ( 1993) ISSN: 1017-5644 [Print] Romania
• PMID: 8011490 (Publication Type: Case Reports, Journal Article)

Topics

• Basal Ganglia Diseases (diagnosis)
• Biopsy
• Cerebellar Diseases (diagnosis)
• Charcot-Marie-Tooth Disease (diagnosis)
• Chronic Disease
• Humans
• Male
• Middle Aged
• Muscles (ultrastructure)
• Paralysis (diagnosis)
• Peripheral Nervous System Diseases (diagnosis)
• Recurrence
• Sural Nerve (ultrastructure)