Abstract |
C-fos proteins were visualized immunohistochemically in the brain of rats after seizures induced by injecting penicillin into hippocampus and by penicillin+electroacupuncture treatment. Three hours following seizures there was an evident expression of c-fos proteins in the hippocampus (CA1 area), dentate gyrus, piriform cortex, dorsal part of entorhinal cortex, and amygdaloid nucleus, and there was a dramatic increase of c-fos proteins in CA3 area and the areas mentioned above except the CA1 area where c-fos proteins apparently decreased after electroacupuncture treatment. The results showed that seizures can induce c-fos proteins in some nuclei related with seizure and that electroacupuncture can also regulates the c-fos expression after seizure.
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Authors | B E Wang, J S Cheng |
Journal | Zhongguo yao li xue bao = Acta pharmacologica Sinica
(Zhongguo Yao Li Xue Bao)
Vol. 15
Issue 1
Pg. 73-5
(Jan 1994)
ISSN: 0253-9756 [Print] China |
PMID | 8010091
(Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Penicillins
- Proto-Oncogene Proteins c-fos
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Topics |
- Animals
- Brain
(metabolism)
- Electroacupuncture
- Epilepsy
(chemically induced, metabolism)
- Female
- Gene Expression Regulation
- Hippocampus
(metabolism)
- Male
- Penicillins
- Proto-Oncogene Proteins c-fos
(biosynthesis, genetics)
- Rats
- Rats, Wistar
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