| Abstract | The case of a 53 year old female patient with metastasized androgen producing adrenocortical carcinoma is presented. After initial adrenalectomy a local relapse had been treated by surgery and external irradiation. Solitary liver metastases had been resected repeatedly. Subsequently multiple liver metastases required systemic chemotherapy. Treatment with o,p'-DDD (initially 12 g/d, long term treatment 1.5-3 g/d) has resulted in a complete remission for nearly 4 years. Gastrointestinal side effects occurred initially but subsided with dose reduction of o,p'-DDD. |
| Authors | E Kornely, R Schlaghecke
(Affiliation: Abteilung für Endokrinologie und Rheumatologie, Heinrich Heine Universität, Düsseldorf, Germany.)
|
| Journal | Experimental and clinical endocrinology
(Exp Clin Endocrinol)
Vol. 102
Issue 1
Pg. 50-3
( 1994)
ISSN: 0232-7384 GERMANY |
| PMID | 8005209
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
|
| Topics |
- Adrenal Cortex Neoplasms
(drug therapy, radiotherapy, surgery)
- Adrenalectomy
- Female
- Humans
- Liver Neoplasms
(drug therapy, secondary)
- Middle Aged
- Mitotane
(administration & dosage, adverse effects, therapeutic use)
- Remission Induction
|
