Descending necrotizing mediastinitis secondary to a retropharyngeal abscess.

A rare case of descending necrotizing mediastinitis (DNM) secondary to a nontraumatic retropharyngeal abscess is reported. Even in the era of antibiotics, the mortality of DNM is still around 40%. In spite of drainage of a localized neck abscess, and the administration of systemic antibiotics, the retropharyngeal abscess extended to the pericardial and pleural cavities. Several drainage procedures and thoracotomies were performed to treat the bilateral empyemas and purulent pericarditis. The patient was discharged on hospital day 52. Computed tomography was used to follow the progression of disease, and assess the efficacy of treatment. DNM is a very aggressive form of mediastinitis. The importance of proper mediastinal drainage, as well as the systemic administration of antibiotics, must be emphasized.
AuthorsM Takao, M Ido, K Hamaguchi, H Chikusa, S Namikawa, M Kusagawa
JournalThe European respiratory journal (Eur Respir J) Vol. 7 Issue 9 Pg. 1716-8 (Sep 1994) ISSN: 0903-1936 [Print] DENMARK
PMID7995405 (Publication Type: Case Reports, Journal Article)
  • Candidiasis (complications)
  • Enterobacter cloacae (isolation & purification)
  • Enterobacteriaceae Infections (complications)
  • Humans
  • Male
  • Mediastinitis (etiology, pathology, therapy)
  • Mediastinum (pathology)
  • Middle Aged
  • Necrosis
  • Retropharyngeal Abscess (complications, microbiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: