Urinary methamphetamine concentration following famprofazone administration.

Abstract

A 37-year-old man had a considerable concentration of methamphetamine in his urine, but he denied taking any abused drug. It was found that he took a pain killer that contains famprofazone, a relatively strong analgesic whose metabolites include methamphetamine and amphetamine. The human urinary metabolism of famprofazone was investigated. Immunoassay was used as a preliminary test, and gas chromatography with flame-ionization detection and gas chromatography-mass spectrometry were used for quantitation and confirmation.

• Authors: Y Yoo, H Chung, H Choi
• Journal: Journal of analytical toxicology (J Anal Toxicol) Vol. 18 Issue 5 Pg. 265-8 (Sep 1994) ISSN: 0146-4760 [Print] England
• PMID: 7990444 (Publication Type: Case Reports, Journal Article)

Chemical References

• Pyrazoles
• Pyrazolones
• Methamphetamine
• Amphetamine
• famprofazone

Topics

• Adult
• Amphetamine (urine)
• Biotransformation
• Chromatography, Gas
• Enzyme Multiplied Immunoassay Technique
• Gas Chromatography-Mass Spectrometry
• Humans
• Male
• Methamphetamine (administration & dosage, analogs & derivatives, metabolism, urine)
• Pyrazoles (administration & dosage, metabolism)
• Pyrazolones