[A resected case of sporadic myxoma of the right ventricle: the diagnosis was supported with DNA flow cytometry].

Abstract

We report a rare case of a 16-year-old male who had myxoma originating from septal band of the right ventricle. His ECG anomaly was found incidentally upon a physical examination. Subsequently, echocardiography and angiocardiography demonstrated a tumor occupying the right ventricular outflow tract and protruding into the main pulmonary artery in systolic phase. He was operated upon using extracorporeal circulation. By right ventriculotomy the tumor was resected together with septal tissue 5 mm around the stalk, which branched into the myocardium. The defect was closed using mattress sutures with Dacron felt strips. We also analyzed the DNA content of the tumor. The DNA flow cytometry yielded a single cell population with diploid DNA content. This result showed that the tumor is sporadic form of cardiac myxoma. His postoperative course was uneventful. Thirty months after the surgery, patient has no sign of recurrence. The DNA flow cytometry is helpful for detecting clinical behavior of the cardiac myxoma, because microscopic examination can not readily distinguish sporadic myxoma from so-called complex myxoma.

• Authors: Y Ueno, K Yanagihara, T Toba, J Isobe, R Inoue, I Nishio, M Yamaguchi, H Uemura, M Ito
• Journal: Kyobu geka. The Japanese journal of thoracic surgery (Kyobu Geka) Vol. 47 Issue 12 Pg. 1020-2 (Nov 1994) ISSN: 0021-5252 [Print] Japan
• PMID: 7990280 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• DNA, Neoplasm

Topics

• Adolescent
• DNA, Neoplasm (analysis)
• Flow Cytometry
• Heart Neoplasms (diagnosis)
• Heart Ventricles
• Humans
• Male
• Myxoma (diagnosis)