Abstract | PURPOSE: PATIENTS AND METHODS: Coagulation and immunology laboratory evaluation was performed at the time of presentation with bleeding and 2 months later, after complete clinical recovery. RESULTS: A 5-year-old girl presented with ecchymoses and a hematoma after after an upper respiratory illness. Laboratory evaluation showed prolongation of both the prothrombin time (PT) and activated partial thromboplastin time (aPTT) due to the presence of a strong lupus anticoagulant associated with a decreased level of prothrombin (15 U/dl). Hypocomplementemia was also detected. Bruising resolved spontaneously, and the PT and aPTT gradually normalized. Reevaluation 2 months later showed that the lupus anticoagulant had disappeared and the prothrombin deficiency was markedly improved. CONCLUSIONS:
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Authors | J E Humphries, M N Acker, J E Pinkston, S Ruddy |
Journal | The American journal of pediatric hematology/oncology
(Am J Pediatr Hematol Oncol)
Vol. 16
Issue 4
Pg. 372-6
(Nov 1994)
ISSN: 0192-8562 [Print] United States |
PMID | 7978060
(Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S., Review)
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Chemical References |
- Lupus Coagulation Inhibitor
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Topics |
- Blood Coagulation
(physiology)
- Child, Preschool
- Female
- Humans
- Hypoprothrombinemias
(blood, immunology)
- Lupus Coagulation Inhibitor
(blood, immunology)
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