[The use of xymedon in treating trophic ulcers of the lower extremities].

Abstract

A new derivative of pyrimidine--Ximedon--was included in the complex treatment of 50 patients with trophic ulcers of lower extremities. The use of Ximedon resulted in shifts of homeostasis, of the cellular composition of the wound discharge, of metabolism of nucleic acids and activity of enzymes of the granulation tissue. Periods of the preoperative preparation of the patients became shorter. The immediate and long-term results obtained after such treatment were more stable.

• Authors: G A Izmaĭlov, G B Evranova, S G Izmaĭlov, S M Gorbunov, T F Rakhmatullina-Miller, L Kh Mavziutov
• Journal: Vestnik khirurgii imeni I. I. Grekova (Vestn Khir Im I I Grek) 1993 Jul-Dec Vol. 151 Issue 7-12 Pg. 43-6 ISSN: 0042-4625 [Print] Russia (Federation)
• Vernacular Title: Ispol'zovanie ksimedona v lechenii troficheskikh iazv nizhnikh konechnosteĭ.
• PMID: 7975017 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Pyrimidines
• xymedon

Topics

• Aged
• Chronic Disease
• Combined Modality Therapy
• Connective Tissue (drug effects, physiology)
• Drug Evaluation
• Female
• Humans
• Middle Aged
• Pyrimidines (therapeutic use)
• Regeneration (drug effects)
• Varicose Ulcer (blood, drug therapy, physiopathology)