[Animal experiment study of tensile strength of hydroxylapatite-coated AO/ASIF Schanz screws for external fixators].

Abstract

The removal torque and the loosening and infection rates of AO/ASIF 4.5 mm Schanz screws (MS) have been compared with those of hydroxyapatite-coated (HA) and hydroxyapatite/silver phosphate-coated (HA/P) AO/ASIF Schanz screws in vivo. In sheep, the left tibia was fixed after a midshaft osteotomy by means of unilateral fixator with 6 Schanz screws in an antero-lateral position. The osteotomy gap was filled with bone wax to avoid bony overgrowth. After operation, the animals were allowed to walk around immediately. The loosening rate was 2.8% at the site of the two HA-coated screws and 36% at the site of the metal screws. The removal torque after 2, 4 and 6 months was 6.2 +/- 2.8 MPa for HA/P, 4.7 +/- 2.7 MPa for HA screws and 1.2 +/- 1.1 MPa for metal screws. Histological and fluoroscopic evaluation revealed intimate bone-HA contact at the cortex near to the fixator, whereas at the site of the metal screws a fibrous tissue layer was constantly found. Only in the cortex opposite to the external fixator a direct bone-metal interface was observed. Fluoroscopic analyses confirmed new bone formation next to the HA surface especially in the cortex adjacent to the fixator, whereas such phenomena were not detected adjacent to the surface of the metal screws. Furthermore, bony resorption around the metal screws (21%) was significantly greater than around the two coated screws (2%). These experimental data suggest that pin loosening can be reduced in external fixators by coating the screws with hydroxyapatite, especially if a long-term fixation is indicated.

• Authors: A Dávid, A Pommer, J Eitenmüller, G Muhr, M P Hahn
• Journal: Der Unfallchirurg (Unfallchirurg) Vol. 97 Issue 8 Pg. 391-8 (Aug 1994) ISSN: 0177-5537 [Print] Germany
• Vernacular Title: Tierexperimentelle Untersuchung zur Haftfestigkeit von Hydroxylapatit-beschichteten AO/ASIF-Schanz-Schrauben für den Fixateur externe.
• PMID: 7973737 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Durapatite

Topics

• Animals
• Bone Screws
• Durapatite
• External Fixators
• Fracture Healing (physiology)
• Sheep
• Surface Properties
• Tensile Strength
• Tibia (pathology, surgery)
• Weight-Bearing (physiology)