Induction of parturition in cattle: effect of triamcinolone pretreatment on the incidence of retained placenta.

Abstract

Two experiments were designed to determine whether pretreatment with triamcinolone acetonide (TRI)prior to induction of parturition with dexamethasone(DEX) and cloprostenol (CLO) would reduce the incidence of retained placenta. Experiment 1 was conducted to determine the optimum dosage of TRI and to approximate the optimum interval from TRI to induction with DEX+CLO. All cows received TRI on day 270 of gestation. Cows in group I received 1 mg/30 kg of body weight (BW) of TRI and were induced to calve with DEX+CLO on day 276. Cows in groups II and III received 1 mg/45 kg BW and were induced on days 276 or 277, respectively. Cows in groups IV and V received 1 mg/60 kg BW and were induced on days 277 or 278, respectively. Group VI cows served as untreated controls. There was no difference in the incidence of retained placenta among the treated and control groups. Experiment 2 was conducted to more precisely determine the optimum interval from pretreatment to induction treatment with the chosen dose of TRI. All cows in groups I, II, and III were pretreated with 1 mg/60 kg BW of TRI on day 270 of gestation and received DEX+CLO on days 275, 276 or 277,respectively. Group IV cows served as untreated controls. The incidence of retained placenta was higher (p < 0.05) in groups I and II than in the control group, with group III intermediate and not different from the others. Cows that retained their placentas had higher (p < 0.05) body temperatures from day 2 to day 7 after calving and tended to have a lower pregnancy rate in the subsequent breeding season than cows that did not retain their placentas.Results indicate that pretreatment with TRI seven days prior to induction of parturition with DEX+CLO resulted in a reduced incidence of retained placenta,apparently by advancing placental maturation.

• Authors: L F Nasser, G A Bo, A D Barth, R J Mapletoft
• Journal: The Canadian veterinary journal = La revue veterinaire canadienne (Can Vet J) Vol. 35 Issue 8 Pg. 491-6 (Aug 1994) ISSN: 0008-5286 [Print] Canada
• PMID: 7954221 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Triamcinolone
• Cloprostenol
• Dexamethasone

Topics

• Animals
• Body Temperature
• Cattle
• Cattle Diseases (etiology, prevention & control)
• Cloprostenol
• Dexamethasone
• Female
• Incidence
• Labor, Induced (adverse effects, veterinary)
• Placenta, Retained (etiology, prevention & control, veterinary)
• Pregnancy
• Premedication (veterinary)
• Treatment Outcome
• Triamcinolone (administration & dosage)