Abstract | BACKGROUND:
Dystrophin, a protein situated on the plasma membrane of skeletal muscle has been found to be abnormal in quality and quantity in patients with muscular dystrophies and may be useful in distinguishing between the different types. Experience with the technique has been limited to western countries. METHODS: We used dystrophin staining with monoclonal NCL-DYS (rod domain) antidystrophin antibody using the avidin- biotin conjugate immunoperoxidase technique in 16 out of 20 patients with various types of muscular dystrophies at a large tertiary care medical centre in India. RESULTS: CONCLUSION:
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Authors | S Jain, C Sarkar, A K Dinda, M C Maheshwari |
Journal | The National medical journal of India
(Natl Med J India)
1993 Nov-Dec
Vol. 6
Issue 6
Pg. 259-62
ISSN: 0970-258X [Print] India |
PMID | 7950930
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Child
- Child, Preschool
- Diagnosis, Differential
- Dystrophin
(analysis)
- Female
- Histocytochemistry
- Humans
- India
- Male
- Middle Aged
- Muscle, Skeletal
(chemistry, pathology)
- Muscular Dystrophies
(diagnosis, metabolism, pathology)
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