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Meckel's diverticulum: possible detection by combining pentagastrin with histamine H2 receptor blocker.

Abstract
A Meckel's scan was performed on a 7-yr-old boy because of rectal bleeding. He was premedicated with pentagastrin (6 micrograms/kg subcutaneously) followed by 259 MBq (7 mCi) [99mTc]pertechnetate intravenously. The study was essentially negative. Because of persistent rectal bleeding and a strong clinical suspicion of a Meckel's, a repeat study was performed 6 wk later. He received pentagastrin as before, but this time was also given a histamine H2 receptor blocker (zantac). A Meckel's diverticulum was clearly evident.
AuthorsS Heyman
JournalJournal of nuclear medicine : official publication, Society of Nuclear Medicine (J Nucl Med) Vol. 35 Issue 10 Pg. 1656-8 (Oct 1994) ISSN: 0161-5505 [Print] United States
PMID7931667 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Ranitidine
  • Sodium Pertechnetate Tc 99m
  • Pentagastrin
Topics
  • Child
  • Gastrointestinal Hemorrhage (etiology)
  • Humans
  • Male
  • Meckel Diverticulum (complications, diagnostic imaging)
  • Pentagastrin
  • Premedication
  • Radionuclide Imaging
  • Ranitidine
  • Rectum
  • Sensitivity and Specificity
  • Sodium Pertechnetate Tc 99m

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