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Biochemical basis of DDT-resistance in Aedes aegypti population from a dengue affected area in Shahjahanpur city.

Abstract
Entomological studies conducted in Jalalnagar, Shahjahanpur city, Uttar Pradesh, India, during an outbreak of dengue in 1992, showed that Ae. aegypti mosquitoes were resistant to DDT and had some tolerance to malathion in the adults and the larvae. Biochemical analysis suggested that DDT resistance was related to elevated glutathione s-transferase and tolerance to malathion was due to a little increase in esterase activity. Crosses of DDT-resistant and susceptible strain suggested that resistance was codominant (metabolic type).
AuthorsD T Mourya, M D Gokhale, A C Mishra
JournalThe Indian journal of medical research (Indian J Med Res) Vol. 99 Pg. 212-5 (May 1994) ISSN: 0971-5916 [Print] India
PMID7927578 (Publication Type: Journal Article)
Chemical References
  • DDT
Topics
  • Aedes (enzymology, genetics)
  • Animals
  • DDT (pharmacology)
  • Dengue (epidemiology)
  • Disease Outbreaks
  • India (epidemiology)
  • Insecticide Resistance (genetics)
  • Urban Health

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