HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Evaluation of treatments for liver abscess: significance of intra-arterial antibiotic injection therapy.

Abstract
Various treatments were performed in 14 patients with liver abscess, and their clinical effects were compared. The treatments were intra-arterial antibiotic infusion therapy (Group A, 4 patients), intra-arterial infusion therapy plus percutaneous drainage of the abscess (Group B, 4 patients), and intravenous antibiotics alone (Group C, 6 patients). The period from the beginning of treatment to negative conversion of CRP* (period until cure) was compared among the groups. Groups A and B had received intravenous antibiotics for a mean of 10 days and 16 days, respectively, but the treatment was ineffective. The mean period until cure from the beginning of intra-arterial infusion therapy was 36 days for Group A and 18 days for Group B. In Group C, the mean period until cure was 28 days. All patients recovered, and recurrence was observed in only one patient. Although liver abscess can be treated successfully in many patients by intravenous antibiotics alone, intra-arterial therapy is effective in those in whom intravenous therapy is not effective.
AuthorsK Sakata, K Hirai, S Itano, M Kajiwara, Y Ijuin, N Ono, H Noguchi, Y Yashiyama, T Yashida, H Yoshida
JournalClinical therapeutics (Clin Ther) 1994 May-Jun Vol. 16 Issue 3 Pg. 446-57 ISSN: 0149-2918 [Print] United States
PMID7923311 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • C-Reactive Protein
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Angiography
  • Anti-Bacterial Agents (administration & dosage, adverse effects, therapeutic use)
  • C-Reactive Protein (metabolism)
  • Female
  • Humans
  • Injections, Intra-Arterial
  • Injections, Intravenous
  • Liver Abscess (diagnostic imaging, drug therapy, microbiology)
  • Male
  • Middle Aged
  • Tomography, X-Ray Computed

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: