Abstract | OBJECTIVE: To determine whether transient ST-T alterations in patients with unstable angina are associated with an increase in plasma glycogen phosphorylase BB concentrations on admission to hospital. DESIGN: Prospective screening of patients with unstable angina for markers of myocardial cell damage. SETTING: Accident and emergency department of university hospital. PATIENTS: MAIN OUTCOME MEASURES: RESULTS: All variables except for creatine kinase and creatine kinase MB activities were significantly higher on admission in patients with unstable angina and transient ST-T alterations than in patients without. However, glycogen phosphorylase BB concentration was the only marker that was significantly (p = 0.0001) increased above its discriminator value in most patients (16). In the 18 patients with transient ST-T alterations creatine kinase MB mass concentration and troponin T and myoglobin concentrations were significantly (p = 0.0001) less commonly increased on admission (in five, three, and two patients, respectively). CONCLUSIONS:
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Authors | J Mair, B Puschendorf, J Smidt, P Lechleitner, F Dienstl, F Noll, E G Krause, G Rabitzsch |
Journal | British heart journal
(Br Heart J)
Vol. 72
Issue 2
Pg. 125-7
(Aug 1994)
ISSN: 0007-0769 [Print] England |
PMID | 7917682
(Publication Type: Journal Article)
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Chemical References |
- Biomarkers
- Isoenzymes
- Phosphorylases
- Creatine Kinase
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Topics |
- Angina, Unstable
(enzymology, physiopathology)
- Biomarkers
(blood)
- Creatine Kinase
(blood)
- Electrocardiography
- Female
- Heart
(physiopathology)
- Humans
- Isoenzymes
(blood, metabolism)
- Male
- Middle Aged
- Phosphorylases
(blood, metabolism)
- Prospective Studies
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