Studies in burns: XV. Use of a topical lipid in treating human burns.

Abstract

Sixty patients were selected from the 24-month burn population admitted to the Medical College of Georgia. Selection was on the basis of age, size of burn, and survival beyond 120 hours. Thirty-one of these patients were treated with ethyl linoleate agent (hELate) in addition to the modalities we routinely use for burn care. hELate was applied in a dose of 25 mg/kg only once in the period after burn. Significant pain relief and enhancement of wound healing (with return of hair and pigment) occurred in the hELate-treated patient. Less narcotic was needed, fewer grafts and reconstructive procedures were required, and hospital stay was reduced significantly. It is suggested that hELate is a safe and useful adjunctive to burn care.

• Authors: C Jelenko 3rd, J C McKinley
• Journal: The American surgeon (Am Surg) Vol. 42 Issue 11 Pg. 838-48 (Nov 1976) ISSN: 0003-1348 [Print] United States
• PMID: 791038 (Publication Type: Case Reports, Clinical Trial, Controlled Clinical Trial, Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Anti-Bacterial Agents
• Linoleic Acids

Topics

• Administration, Topical
• Adult
• Anti-Bacterial Agents (administration & dosage)
• Blast Injuries (drug therapy)
• Burns (drug therapy, surgery)
• Burns, Chemical (drug therapy)
• Clinical Trials as Topic
• Debridement
• Drug Therapy, Combination
• Female
• Humans
• Linoleic Acids (administration & dosage)
• Male
• Middle Aged
• Pain (drug therapy)
• Postoperative Care
• Skin Transplantation
• Transplantation, Autologous
• Wound Healing (drug effects)