Abstract | OBJECTIVES: DESIGN: SETTING: Newcastle, Australia. SUBJECTS: MAIN OUTCOME MEASURES: RESULTS: CONCLUSIONS:
Pheniramine is taken in overdose more frequently than other antihistamines relative to its market share. It is also more likely to be abused than other antihistamines. In overdose, it appears to be more proconvulsant than other antihistamines. Consideration should be given to the use of alternative antihistamines in patients at risk of seizures. In the light of these findings, regulatory authorities should review the over-the-counter availability of pheniramine.
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Authors | N A Buckley, I M Whyte, A H Dawson, D A Cruickshank |
Journal | The Medical journal of Australia
(Med J Aust)
Vol. 160
Issue 4
Pg. 188-92
(Feb 21 1994)
ISSN: 0025-729X [Print] Australia |
PMID | 7906008
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Histamine H1 Antagonists
- Pheniramine
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Topics |
- Adult
- Drug Overdose
- Female
- Follow-Up Studies
- Histamine H1 Antagonists
(poisoning)
- Humans
- Male
- Odds Ratio
- Pheniramine
(poisoning)
- Poisoning
(complications)
- Seizures
(etiology)
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