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Efficacy of ivermectin for the treatment of head lice (Pediculosis capitis).

Abstract
Twenty six male and female patients aged 5 to 17 years who had head lice infestation confirmed by eggs presence and received treatments with a single 200 mu/kg oral dose of ivermectin in open fashion. At day 14 after treatment, 20 responded to the treatment (77%), and 6 patients (23%) presented with a complete disappearance of eggs and all clinical symptoms. At day 28, 7 patients were healed (27%), but 4 patients of the 6 healed at day 14 presented with signs of reinfestation. This study suggests that ivermectin is a promising treatment of head lice, and a second dose at day 10 should be appropriate for a further comparative trial.
AuthorsP Glaziou, L N Nyguyen, J P Moulia-Pelat, J L Cartel, P M Martin
JournalTropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ) (Trop Med Parasitol) Vol. 45 Issue 3 Pg. 253-4 (Sep 1994) ISSN: 0177-2392 [Print] Germany
PMID7899799 (Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Ivermectin
Topics
  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Ivermectin (therapeutic use)
  • Lice Infestations (drug therapy)
  • Male
  • Pilot Projects
  • Scalp Dermatoses (drug therapy)

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