Abstract |
Esthesioneuroblastoma is an uncommon tumour of neural crest origin arising in the nasal cavity. This paper is a retrospective review of 7 patients with esthesioneuroblastoma treated at a single institution from May 1974 to July 1990. 5 patients were treated with radiation therapy alone and 2 patients were irradiated after surgical resection. No local or regional occurrence was observed in any patient at 6 months, or at 1, 3, 6, 11.5 and 12 years following treatment. One patient died of intercurrent disease 6 years after radiation therapy. 2 patients died of disease, 1 of distant metastasis at 6 months and the other patient of meningeal carcinomatosis and distant metastases 1 year after treatment. One patient is alive with distant metastases 1 year after treatment. None of the patients experienced significant complications of irradiation. High-dose irradiation (60 Gy or more) alone or in combination with resection is an effective local treatment modality for esthesioneuroblastoma.
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Authors | F Guedea, E Van Limbergen, W Van den Bogaert |
Journal | European journal of cancer (Oxford, England : 1990)
(Eur J Cancer)
Vol. 30A
Issue 12
Pg. 1757-60
( 1994)
ISSN: 0959-8049 [Print] England |
PMID | 7880600
(Publication Type: Journal Article)
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Topics |
- Adolescent
- Adult
- Aged
- Combined Modality Therapy
- Esthesioneuroblastoma, Olfactory
(radiotherapy, secondary, surgery)
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Nasal Cavity
- Nose Neoplasms
(radiotherapy, surgery)
- Radiotherapy Dosage
- Radiotherapy, High-Energy
- Retrospective Studies
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