| Abstract | The microbiological study of vaginal secretions of 39 female patients of reproductive age (20-30 years) with papilloma virus infection associated with cervical intraepithelial neoplasia (CIN) was carried out. Of these patients, 28 with papilloma virus infection associated with CINI-II made up group I and II having this infection associated with CINII made up group 2. Dysbiotic disturbances in vaginal bacterial flora, found in these patients, were manifested by a decrease in the isolation rate and number of the lacto- and bifidobacteria simultaneously with the excessive growth of opportunistic bacteria. The results of the oral administration of Solco-Trichovac are indicative of the effectiveness of this preparation, which was confirmed by the data of clinical and bacteriological studies. Together with an increase in the isolation rate of lacto- and bifidobacteria, the level of the contamination of the cervicovaginal niche with opportunistic and pathogenic bacterial strains decreased. The results thus obtained make it possible to recommend Solco-Trichovac for the complex treatment of with papilloma virus infection associated with CIN. |
| Authors | V M Korshunov, L I Kafarskaia, M Sh Bagirova, G N Minkina, I B Manukhin, W Bossart |
| Journal | Zhurnal mikrobiologii, epidemiologii, i immunobiologii
(Zh Mikrobiol Epidemiol Immunobiol)
1994 Sep-Oct
Issue 5
Pg. 13-7
ISSN: 0372-9311 RUSSIA |
| Vernacular Title | Izuchenie vliianiia "Solkotrikhovaka" na vaginal'nuiu mikrofloru u bol'nykh s papillomavirusnoĭ infektsieĭ v assotsiatsii s tservikal'noĭ intraépitelial'noĭ neoplazieĭ. |
| PMID | 7879473
(Publication Type: Comparative Study, English Abstract, Journal Article)
|
| Chemical References |
- Adjuvants, Immunologic
- Bacterial Vaccines
- SolcoTrichovac
|
| Topics |
- Adjuvants, Immunologic
(therapeutic use)
- Adult
- Bacterial Vaccines
(therapeutic use)
- Cervical Intraepithelial Neoplasia
(drug therapy, virology)
- Condylomata Acuminata
(drug therapy, microbiology)
- Drug Evaluation
- Female
- Humans
- Lactobacillus
- Papillomaviridae
- Papillomavirus Infections
(drug therapy, virology)
- Tumor Virus Infections
(drug therapy, virology)
- Uterine Cervical Diseases
(drug therapy, virology)
- Uterine Cervical Neoplasms
(drug therapy, virology)
- Vagina
(drug effects, virology)
|
