[The effect of SolcoTrichovac on the vaginal microflora of patients with a papillomavirus infection associated with a cervical intraepithelial neoplasm].

Abstract

The microbiological study of vaginal secretions of 39 female patients of reproductive age (20-30 years) with papilloma virus infection associated with cervical intraepithelial neoplasia (CIN) was carried out. Of these patients, 28 with papilloma virus infection associated with CINI-II made up group I and II having this infection associated with CINII made up group 2. Dysbiotic disturbances in vaginal bacterial flora, found in these patients, were manifested by a decrease in the isolation rate and number of the lacto- and bifidobacteria simultaneously with the excessive growth of opportunistic bacteria. The results of the oral administration of Solco-Trichovac are indicative of the effectiveness of this preparation, which was confirmed by the data of clinical and bacteriological studies. Together with an increase in the isolation rate of lacto- and bifidobacteria, the level of the contamination of the cervicovaginal niche with opportunistic and pathogenic bacterial strains decreased. The results thus obtained make it possible to recommend Solco-Trichovac for the complex treatment of with papilloma virus infection associated with CIN.

• Authors: V M Korshunov, L I Kafarskaia, M Sh Bagirova, G N Minkina, I B Manukhin, W Bossart
• Journal: Zhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) 1994 Sep-Oct Issue 5 Pg. 13-7 ISSN: 0372-9311 [Print] Russia (Federation)
• Vernacular Title: Izuchenie vliianiia "Solkotrikhovaka" na vaginal'nuiu mikrofloru u bol'nykh s papillomavirusnoĭ infektsieĭ v assotsiatsii s tservikal'noĭ intraépitelial'noĭ neoplazieĭ.
• PMID: 7879473 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Bacterial Vaccines
• SolcoTrichovac

Topics

• Adjuvants, Immunologic (therapeutic use)
• Adult
• Bacterial Vaccines (therapeutic use)
• Condylomata Acuminata (drug therapy, microbiology)
• Drug Evaluation
• Female
• Humans
• Lactobacillus
• Papillomaviridae
• Papillomavirus Infections (drug therapy, virology)
• Tumor Virus Infections (drug therapy, virology)
• Uterine Cervical Diseases (drug therapy, virology)
• Uterine Cervical Neoplasms (drug therapy, virology)
• Vagina (drug effects, virology)
• Uterine Cervical Dysplasia (drug therapy, virology)