Detection of medullary carcinoma of the thyroid with I-131 MIBG.

Abstract

Imaging with I-131 MIBG has proved useful for the detection of pheochromocytoma, neuroblastoma, and other neoplasms of neural crest origin. The authors present a case of a patient who was initially diagnosed as having follicular carcinoma of the thyroid in which I-131 MIBG played a key role in leading to the diagnosis of medullary carcinoma of the thyroid. Local and distant metastases were detected using I-131 MIBG imaging. Uptake of I-131 MIBG by medullary carcinoma of the thyroid has both diagnostic and therapeutic implications.

• Authors: C C Thomas, R J Cowan, D A Albertson, M R Cooper
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 19 Issue 12 Pg. 1066-8 (Dec 1994) ISSN: 0363-9762 [Print] United States
• PMID: 7874804 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antineoplastic Agents
• Iodine Radioisotopes
• Iodobenzenes
• 3-Iodobenzylguanidine
• Technetium Tc 99m Sulfur Colloid

Topics

• 3-Iodobenzylguanidine
• Adenocarcinoma, Follicular (diagnosis)
• Antineoplastic Agents (therapeutic use)
• Carcinoma, Medullary (diagnostic imaging, secondary, therapy)
• Humans
• Iodine Radioisotopes (therapeutic use)
• Iodobenzenes (therapeutic use)
• Liver Neoplasms (diagnostic imaging, secondary)
• Male
• Middle Aged
• Radionuclide Imaging
• Technetium Tc 99m Sulfur Colloid
• Thyroid Neoplasms (diagnostic imaging, pathology, therapy)