Effect of sodium amylosulfate (Depepsen) on the healing of duodenal ulcer.

Abstract

Thirty-five patients with active duodenal ulceration were included in a double blind randomized trial, the antiulcer agent sodium amylosulfate (Depepsen), being compared with placebo. Diagnosis and healing were determined by duodenoscopy. Results showed, in the whole series, 13 of 18 patients treated with Depepsen healed, whereas 10 of 17 healed on placebo (P = 0.04). In the group of 23 outpatients, 6 of 11 healed on Depepsen, and 5 of 12 healed on placebo (P = 0.55). It was concluded that Depepsen did not accelerate the healing of duodenal ulcer.

• Authors: K D Landecker, E M McCallum, D I Fevre, R Green, A Kasumi, D W Piper
• Journal: Gastroenterology (Gastroenterology) Vol. 71 Issue 5 Pg. 723-5 (Nov 1976) ISSN: 0016-5085 [Print] United States
• PMID: 786772 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Amylopectin

Topics

• Adult
• Aged
• Ambulatory Care
• Amylopectin (therapeutic use)
• Clinical Trials as Topic
• Duodenal Ulcer (drug therapy)
• Female
• Hospitalization
• Humans
• Male
• Middle Aged
• Wound Healing (drug effects)