HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

On the significance of cholecystokinin receptors in panic disorder.

Abstract
Interest in the biological aspects of panic disorder has been focussed mainly on the noradrenergic and serotonergic systems in the brain. Recently evidence has been found that Cholecystokinin (CCK) receptors in the Central Nervous System (CNS) may be involved in panic disorders. This hypothesis is based on the results of animal electrophysiological studies, animal models of anxiety and on challenge test using CCK fragments in humans. In this review, the studies evaluating the putative involvement of CCK, and especially CCK-B receptors, in panic disorder will be discussed.
AuthorsH J van Megen, J A den Boer, H G Westenberg
JournalProgress in neuro-psychopharmacology & biological psychiatry (Prog Neuropsychopharmacol Biol Psychiatry) Vol. 18 Issue 8 Pg. 1235-46 (Dec 1994) ISSN: 0278-5846 [Print] England
PMID7863014 (Publication Type: Journal Article, Review)
Chemical References
  • Receptors, Cholecystokinin
  • Cholecystokinin
Topics
  • Animals
  • Behavior, Animal (drug effects)
  • Cholecystokinin (pharmacology, physiology)
  • Clinical Trials as Topic
  • Dose-Response Relationship, Drug
  • Humans
  • Panic Disorder (drug therapy, physiopathology)
  • Rats
  • Receptors, Cholecystokinin (physiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: