Suppressive effects of eugenol and ginger oil on arthritic rats.

Abstract	This study examined the effect of eugenol and ginger oil on severe chronic adjuvant arthritis in rats. Severe arthritis was induced in the right knee and right paw of male Sprague-Dawley rats by injecting 0.05 ml of a fine suspension of dead Mycobacterium tuberculosis bacilli in liquid paraffin (5 mg/ml). Eugenol (33 mg/kg) and ginger oil (33 mg/kg), given orally for 26 days, caused a significant suppression of both paw and joint swelling. These findings suggest that eugenol and ginger oil have potent antiinflammatory and/or antirheumatic properties.
Authors	J N Sharma, K C Srivastava, E K Gan
Journal	Pharmacology (Pharmacology) Vol. 49 Issue 5 Pg. 314-8 (Nov 1994) ISSN: 0031-7012 [Print] Switzerland
PMID	7862743 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Anti-Inflammatory Agents, Non-Steroidal Eugenol
Topics	Animals Anti-Inflammatory Agents, Non-Steroidal (therapeutic use) Arthritis, Experimental (drug therapy, etiology) Eugenol (therapeutic use) Male Mycobacterium tuberculosis Rats Rats, Sprague-Dawley Spices

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